Table 4.

Measurements of airway inflammatory markers, nitrite/nitrate (NOX), interleukin-8 (IL-8), 8-isoprostanes (8iso), hydrogen peroxide (H2O2) in patients treated with CPAP and sham CPAP.

	NOX (μmol/l)	IL- 8 (pg/ml)	8iso (pg/ml)	H2O2 nmol/L
CPAP – treated (n=9)
Baseline	3.34 ± 2.07	1.52 ± 1.41	4.92 ± 2.23	2458.02 ± 324.88
Post-6 weeks	2.91 ± 2.32	1.00 ± 0.21	7.35 ± 3.47	1654.07 ± 239.71
p value*	0.685	0.299	0.212	0.097
Sham CPAP – treated (n=8)
Baseline	3.35 ± 2.81	1.02 ± 0.24	3.99 ± 1.89	1714.42 ± 337.1
Post-6 weeks	5.26 ± 0.18	1.04 ± 0.18	5.04 ± 2.13	1468.04 ± 143.58
p value*	0.334	0.771	0.199	0.061
Difference between CPAP – treated and sham CPAP – treated groups (p value#)	0.258	0.594	0.156	0.643

For comparing intragroup change with either CPAP or sham-CPAP therapy, p value* was calculated using paired-sample t test for measurement of significant differences of means. For differences of change after 6 weeks of either CPAP or sham-CPAP therapy, p value^# was calculated using ANCOVA that adjusted for baseline values of each marker.