Table 4.
Comparison of Aberrant Myeloid Antigen Expression and CD34 Expression in ALL in Literature
| Serial number |
Ethnicity | Age group (years) | Number of patients | MyAg studied | Correlation between MyAg and CD34 | p-value* |
|---|---|---|---|---|---|---|
| 1. Mi et al (1999) | Chinese | Adult | 102 | NA | Not found in ALL and B-ALL | NA |
| 2. Yeneral et al (2002) | Turkish | Adult (14-62) |
46 | CD13, CD33 | Not found in ALL | 0.06 |
| 3. Vitale et al (2007) | European (Rome) | Adult (14-60) |
377 | CD13, CD33 | Present between MyAg+ and CD34+ in ALL | <0.0001* |
| 4. Tong et al (2010) | Chinese | All (1-72) |
113 | CD13, CD33, CD15, CD117 | Present between MyAg+ and CD34+ in ALL | 0.002* |
| 5. Tong et al (2011) | Chinese | Pediatric (0-14) | 207 | CD13, CD33, CD15, CD117 | Present between MyAg+ and CD34+ in ALL | 0.004* |
| 6. Tong et al (2014) | Chinese | Adult (15-77) |
110 | CD13, CD33, CD15, CD117 | Present between MyAg+ and CD34+ in ALL | 0.019* |
| 7. Sharma et al (2014) | Indian | All (2-61) |
ALL (204) B-ALL (163) | CD13, CD33, CD117 | Present between MyAg+ and CD34high in ALL and B-ALL | 0.0001* (in both ALL and B-ALL) |
| 8. Sharma et al (2016) | Indian | All (<1-65) |
Adult (96), Pediatric (207) | CD13, CD33, CD117 | Present between MyAg+ and CD34+ in ALL | p=0.001* (Adult), p=0.0004* (Pediatric) |
| 9. Present study (2020) | Indian | All | 75 | CD13, CD33 | Not found in B-ALL | 0.051 |
NA, Not available; My, Myeloid antigen expression; My+, Myeloid antigen positivity; ALL, Acute lymphoblastic leukemia; B-ALL, B- acute lymphoblastic leukemia; *p<0.05 is statistically significant