Table 1.
Subject Characteristics (n=107)
| Variable | Total (n=107) | With seizure (n=25) | No seizure (n=82) | p-value |
|---|---|---|---|---|
| Age, mean in years (SD) | 39.77(19.04) | 36.32(17.77) | 40.82 (19.39) | 0.173# |
| Sex, n (%) | ||||
| Male | 60 (56.07) | 13 (52) | 47 (57.32) | 0.639 |
| Female | 47 (43.93) | 12 (48) | 35 (42.68) | |
| A history of smoking, n (%) | ||||
| Yes | 27 (28.13) | 9 (39.13) | 18 (24.66) | 0.178 |
| No | 69 (71.87) | 14 (60.87) | 55(75.34) | |
| Tumor location (include this lobe/not) | ||||
| Frontal | 29/57 | 11/10 | 18/47 | 0.037 |
| Temporal | 41/45 | 12/9 | 29/36 | 0.318 |
| Parietal | 42/44 | 8/13 | 34/31 | 0.257 |
| Occipital | 9/77 | 3/18 | 6/59 | 0.682## |
| Others | 14/72 | 1/20 | 13/52 | 0.172## |
| Tumor side, n (%) | ||||
| Left | 39 (100) | 9 (23.08) | 30 (76.92) | 0.510 |
| Right | 30 (100) | 10 (33.33) | 20 (66.67) | 0.262 |
| Bilateral | 7 (100) | 1 (14.29) | 6 (85.71) | 0.668## |
| Histological type, n (%) | ||||
| Astrocytoma | 85 (100) | 19 (22.35) | 66 (77.65) | 0.627## |
| Oligoastrocytoma | 5 (100) | 1 (20) | 4 (80) | 1## |
| Oligodendroglioma | 9 (100) | 5 (55.56) | 4 (44.44) | 0.031## |
| Ependymoma | 8 (100) | 0 (0) | 8 (100) | 0.194## |
| Grade, n (%) | ||||
| Grade I | 7 (6.54) | 1 (4) | 6 (7.32) | 0.406## |
| Grade II | 34 (31.78) | 8 (32) | 26 (31.71) | |
| Grade III | 22 (20.56) | 8 (32) | 14 (17.07) | |
| Grade IV | 44 (41.12) | 8 (32) | 36 (43.9) | |
| Combined grade, n (%) | ||||
| Grade I & II (low grade) | 38 (35.51) | 7 (28) | 31 (37.8) | 0.37 |
| Grade III & IV (high grade) | 69 (64.49) | 18 (72) | 51 (62.2) | |
| Ki-67, mean (SD) | 16.71 (16.54) | 16.45 (15.17) | 16.81 (17.16) | 0.740# |
| IDH1 mutation | ||||
| Wild type | 87 (82.86) | 18 (72) | 69 (86.25) | 0.128## |
| Mutant | 18 (17.14) | 7 (28) | 11 (13.75) | |
| MGMT promoter methylation, n (%) | ||||
| Methylated | 13 (22.41) | 4 (30.77) | 9 (20) | 0.460## |
| Unmethylated | 45 (77.59) | 9 (69.23) | 36 (80) |
#, Mann-Whitney U test; ##, Fisher exact test; Chi-square tests were performed for the rest of the analyses.