Table 3.

MIDAS Items According to Number of Lines of Preventive Treatments Ever Received

	US					EU
	Overall (n=827)	PN (n=501)	1–2 Lines (n=307)	3+ Lines (n=19)	P Value	Overall (n=1971)	PN (n=1206)	1–2 Lines (n=727)	3+ Lines (n=38)	P Value
Total score	N=688	N=404	N=267	N=17	<0.0001	N=1628	N=997	N=604	N=27	<0.0001
Mean (SD)	8.1 (14.8)	6.1 (9.8)	9.6 (18.6)	30.4 (25.0)		11.0 (16.2)	8.8 (12.0)	13.8 (20.1)	31.6 (28.6)
In the last 3 months, on how many days...a
Did you miss work or school	N=763	N=457	N=289	N=17	<0.0001	N=1803	N=1104	N=665	N=34	0.0833
Mean (SD)	1.0 (1.9)	0.7 (1.4)	1.2 (2.2)	3.7 (4.2)		1.2 (3.3)	1.1 (2.5)	1.3 (4.3)	2.1 (2.6)
Was your productivity at work/school reduced by >50%	N=755	N=449	N=289	N=17	<0.0001	N=1733	N=1061	N=642	N=30	<0.0001
Mean (SD)	1.6 (3.4)	1.3 (2.9)	1.7 (3.4)	6.7 (7.6)		2.1 (4.3)	1.7 (3.3)	2.7 (5.5)	4.3 (5.6)
Did you not do household work	N=745	N=447	N=279	N=19	<0.0001	N=1842	N=1120	N=687	N=35	<0.0001
Mean (SD)	2.4 (6.1)	1.7 (3.1)	3.1 (8.9)	7.5 (5.6)		2.9 (5.4)	2.3 (4.6)	3.6 (6.2)	6.9 (8.3)
Was your productivity in household work reduced by >50%	N=733	N=430	N=284	N=19	<0.0001	N=1803	N=1095	N=675	N=33	<0.0001
Mean (SD)	2.5 (5.8)	1.9 (4.4)	3.1 (7.2)	9.2 (7.4)		3.2 (5.5)	2.4 (4.2)	4.0 (6.3)	11.2 (13.0)
Did you miss family/social/leisure activities	N=768	N=459	N=290	N=19	<0.0001	N=1862	N=1134	N=692	N=36	<0.0001
Mean (SD)	1.4 (2.6)	1.0 (1.9)	1.8 (3.2)	3.6 (4.0)		2.3 (3.4)	1.8 (2.8)	2.8 (3.7)	7.6 (7.8)

Notes: ^aDue to headaches. P-values are from ANOVA and are for comparison across groups.

Abbreviations: PN, preventive-naïve; SD, standard deviation.