Table 2.
Overview of data collection Acutelines biobank
| Data and biomaterials | <1 year – ED visit | Prehospital | ED – 72 hours | 3 months | 1 year | 2 years | 5 years | ∞ | |
| Contact info and deferred consent | √ | Consent within 30 days and opt-out (if unreachable) | |||||||
| Meta data ED visit (ie, referral, mode of transport, triage category, length of stay, decision making, final disposition) | √ | ||||||||
| Presenting complaints | √ | √ | |||||||
| Demographic data (ie, gender, age, living situation, mortality, country of origin) | √ | √ | √ | √ | √ | √ | √ | ||
| Medical (family) history | √ | ||||||||
| Medication use and intoxications | √ | √ | √ | √ | √ | √ | ATC level 1, 3 and 5 as defined daily dose | ||
| Non-pharmacological treatment | √ | √ | |||||||
| Vital parameters, physical examination and disease severity | √ | √ | |||||||
| ECG | √ | √ | |||||||
| Radiological results | √ | Including point-of-care ultrasound | |||||||
| Biometry | √ | Photograph or movie (<10 s) of face to capture clinical impression | |||||||
| Laboratory results (full) | √ | √ | |||||||
| Laboratory results (core set) | √ | √ | √ | √ | √ | √ | √ | Kidney and liver function, lipid profile, albumin, cardiac markers, ESR and CRP | |
| Health status | √ | √ | √ | Nutrition, Karnofsky, EQ-5D-5L, PHQ-2, PHQ-15, Katz ADL-15(if Karnofsky<70) | |||||
| Frailty screening (if age >65 years) |
√ | APOP | |||||||
| Fatigue | √ | √ | Piper fatigue scale | ||||||
| Mood and depression (if PHQ-2 positive) |
√ | √ | √ | PHQ-9 (if age ≥70 years: GDS-15) | |||||
| Cognitive function (if age ≥70 years) |
√ | √ | √ | 4AT (in hospital), 6-CIT (in hospital), DOS (in hospital) | |||||
| Physical activities (if karnofsky >70) |
√ | √ | √ | SQUASH | |||||
| Biomaterials (plasma, serum, buffy coat, RNA, faeces, urine, hair) | √ | If triage colour red or orange (hair only if COPD/asthma exacerbation) |
A visual overview of data to be collected is presented in online supplemental figures 1 and 2.
APOP, Acuut Presenterende Oudere Patient (Acute Presenting Elderly Patient); 4AT, 4 ‘A’s delirium Test; ATC, Anatomical Therapeutic Chemical Classification system; 6-CIT, 6 item Cognitive Impairment Test; CRP, C reactive protein; DOS, delirium observation screening; ED, emergency department; EQ-5D-5L, 5-level EQ-5D test; ESR, Erythrocyte Sedimentation Rate; GDS-15, Geriatric Depression Score; PHQ-2/9/15, Patient Health Questionnaire-2/15; RNA, ribonucleic acid; SQUASH, Short Questionnaire to Assess Health-enhancing physical activity.