Table 3.

Projected cases of active tuberculosis, associated costs and length of stay threshold with screening migrants with different LTBI treatment regimens

Treatment regimens	No of TB cases over 50 years per 10 000 screened	No of TB cases averted over 50 years	Cost over 50 years (SGD)	Incremental cost over 50 years (SGD)	ICER (SGD/TB case averted)	QALYs	Incremental QALYs	ICER (SGD/QALY)	Threshold for Length of Stay (years)
No screen and treat	234.42		1 563 135			260 220.28
3 Months INH+RPT	78.54	155.88	3 499 458	1 936 323.58	12 421.89	260 254.18	33.90	57 116.31	43.92
4 months RIF	102.13	132.28	3 614 640	2 051 505.29	15 508.28	260 249.44	29.17	70 340.28	47.52
6 months INH	121.17	113.25	3 976 948	2 413 812.76	21 314.61	260 242.37	22.09	109 261.44	56.12
9 months INH	110.62	123.79	4 303 918	2 740 782.84	22 139.73	260 242.92	22.65	121 010.88	57.94

INH, isoniazid; LTBI, latent tuberculosis infection; QALYs, quality-adjusted life-years; RIF, rifampicin; RPT, rifapentine; SGD, Singapore dollars.