Figure 2.

SARS-CoV-2-reactive T-cell responses

Peripheral blood mononuclear cells were stimulated with peptide pools of cytomegalovirus pp65(CMV), structural proteins of SARS-CoV-2 (membrane, nucleocapsid, and spike). Twenty-two hours later, antigen-specific T-cell activation was analyzed by flow cytometry. Dot plots show activated CD4⁺ T and CD8⁺ T-cells identified as CD137⁺OX40⁺and CD137⁺CD69⁺ cells, respectively.