Table 1. Inhibitory activity of compounds against SARS-CoV-2 RdRp in vitro.
Compound name | IC50 (µM) | ||
---|---|---|---|
No detergent | + 0.01% Triton X-100 | Data figure | |
Suramin1 | 0.43 | 0.78 | 4 |
C646 | 6.1 | 7.8 | 4 |
BH3I-1 | 14 | 13 | 4 |
GSK-650394 | 31 | 29 | 4 |
MDK-83190 | 42 | 56 | 4 |
Cefsulodin | 50 | 49 | 4 |
For a further characterisation of suramin and the suramin-related compounds NF 023, PPNDS, Evans Blue, Diphenyl Blue see Zeng et al. [46].