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. 2021 Jul 2;478(13):2425–2443. doi: 10.1042/BCJ20210200

Table 1. Inhibitory activity of compounds against SARS-CoV-2 RdRp in vitro.

Compound name IC50 (µM)
No detergent + 0.01% Triton X-100 Data figure
Suramin1 0.43 0.78 4
C646 6.1 7.8 4
BH3I-1 14 13 4
GSK-650394 31 29 4
MDK-83190 42 56 4
Cefsulodin 50 49 4
1

For a further characterisation of suramin and the suramin-related compounds NF 023, PPNDS, Evans Blue, Diphenyl Blue see Zeng et al. [46].