Table 2. Inflammasome-forming pattern recognition receptors.
Pattern recognition receptor | Examples of activating stimuli |
---|---|
NLRP1 | Proteases from pathogens [39,40] |
viral dsRNA [41] | |
Toxoplasma gondii [42] | |
NLRP3 | Pore-forming toxins (Hemolysin, Candidalysin) [43,44] |
B-glucan [45] | |
ATP [46] | |
Urate crystal [47] | |
NLRP6 | Lipoteichoic acid (LTA) [48] |
NLRP7 | Lipopeptide [49] |
NLRC4/NAIP | T3SS proteins, Flagellin [50] |
AIM2 | Cytosolic DNA [51,52] |
Pyrin | Rho GTPase inactivation [53] |
GBPs | LPS [54–56] |