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. 2021 Jun 1;49(3):1311–1324. doi: 10.1042/BST20200986

Table 2. Inflammasome-forming pattern recognition receptors.

Pattern recognition receptor Examples of activating stimuli
NLRP1 Proteases from pathogens [39,40]
viral dsRNA [41]
Toxoplasma gondii [42]
NLRP3 Pore-forming toxins (Hemolysin, Candidalysin) [43,44]
B-glucan [45]
ATP [46]
Urate crystal [47]
NLRP6 Lipoteichoic acid (LTA) [48]
NLRP7 Lipopeptide [49]
NLRC4/NAIP T3SS proteins, Flagellin [50]
AIM2 Cytosolic DNA [51,52]
Pyrin Rho GTPase inactivation [53]
GBPs LPS [54–56]