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. 2021 Jul 2;478(13):2465–2479. doi: 10.1042/BCJ20210199

Figure 5. NSC95397 does not inhibit SARS-CoV-2 growth in VERO cells.

Figure 5.

(A) SARS-CoV-2 infectivity assays in the presence of NSC95397. DNA in cells was stained with DRAQ5, and virus was immunostained with anti-N antibody. (B) Quantification of normalised viral area (black) and cell area (gray) ±SD. Both viral and cell area was normalised to control condition (DMSO) and, viral area was also normalised to cell area (see Experimental Procedures for details). (C) SARS-CoV-2 infectivity assays as in A with lower concentrations of NSC95397. (D) Quantification of C as in B. (E) SARS-CoV-2 infectivity assays as in C in the presence of 0.5 µM remdesivir. (F) Quantification of E as in B, note that black control line is quantification of control experiment in C.