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. 2021 Jul 2;478(13):2499–2515. doi: 10.1042/BCJ20210197

Table 1. Primary hit list.

Compound Cas No Fluorescence % Reduction at 4 µM % Reduction at 0.8 µM
Z-DEVD-FMK 210344-95-9 normal 100 53
Z-IETD-FMK 210344-98-2 normal 100 50
Z-VAD(OMe)-FMK 187389-52-2 normal 100 43
Adapalene 106685-40-9 HIGH 87 0
Prazosin hydrochloride 19237-84-4 HIGH 80 0
CH-223191 301326-22-7 normal 79 0
3,9-dihydroxy-2-(3-methyl-2-butenyl)-6H-[1]benzofuro[3,2-c]chromen-6-one 18642-23-4 HIGH 79 0
JD-5037 1392116-14-1 HIGH 74 0
Go6976 136194-77-9 moderate 67 0
Tariquidar 206873-63-4 HIGH 66 0
ETP-46464 1345675-02-6 HIGH 64 0
PDK1/Akt/Flt Dual Pathway Inhibitor 331253-86-2 moderate 64 0
Doxazosin (mesylate) 77883-43-3 HIGH 60 0
NVP-BVU972 1185763-69-2 HIGH 59 0
2S)-2-(acetylamino)-N-[(1S)-1-({[(1S)-1-formylpentyl]amino}carbonyl)-3-methylbutyl]-4-methylpentanamid 110044-82-1 normal 58 0
Marbofloxacin 115550-35-1 moderate 56 0
STF-118804 894187-61-2 HIGH 55 0
CPI-613 95809-78-2 HIGH 54 0
Bromoenol lactone 88070-98-8 normal 49 0
Fatostatin HBr 298197-04-3 normal 48 0
Sotagliflozin (LX4211) 1018899-04-1 normal 47 0
Tyrphostin AG 1296 146535-11-7 moderate 45 0
Alfuzosin 81403-80-7 HIGH 44 0
Palomid 529 914913-88-5 HIGH 43 0
1-Allyl-3,7-dimethyl-8-p-sulfophenylxanthine 149981-25-9 moderate 37 0
Granisetron HCl 107007-99-8 HIGH 36 0
Curcumol 4871-97-0 HIGH 31 0