Table 1. Percentage of inhibition and Z score on hits from screening.
No. | Name | Inhibition (%) | Z score | |
---|---|---|---|---|
3.75 µM (slope value/control) | 1.25 µM (slope value/control) | |||
1 | PDK1/Akt/Flt Dual Pathway Inhibitor | 100 (0/491) | 89 (50/452) | −14.53 |
2 | Ursodiol | 55 (187/420) | 26 (324/440) | −7.78 |
3 | Pyrocatechuic acid | 49 (226/444) | 0 (453/441) | −6.846 |
4 | Ro 08-2750 | 42 (287/491) | 19 (366/452) | −5.79 |
5 | Cdk4 Inhibitor III | 39 (302/491) | 19 (367/452) | −5.34 |
6 | beta-Lapachone | 34 (322/486) | 7 (420/453) | −4.66 |
7 | Dihydrotanshinone I | 33 (329/490) | 0 (449/440) | −4.52 |