Table S1. P values for comparison of IS-mod (3- and 2-category) and IS-mod using 25% and 70% as thresholds.

Variables	Discovery cohort				Validation cohort
	C-index	AUC at 5-year	iAUC		C-index	AUC at 5-year	iAUC
IS, Immunoscore; IS-mod, modified Immunoscore; IS-mod25%,70%, 3-category IS-mod using 25% and 70% as thresholds; IS-mod25%, 2-category IS-mod using 25% as threshold; AUC, area under the receiver operating characteristic curve; iAUC, integrated AUC.
IS-mod (3-category) vs. IS-mod25%,70%	0.029	0.007	<0.001		0.283	0.080	0.970
IS-mod (2-category) vs. IS-mod25%	0.004	0.002	<0.001		0.021	0.012	<0.002