Table 3.
Cohort 1-4F comparisons and ranking of selected Image Quality (IQ) parameters
| Cohort | Reader 1 (R1) | Reader 2 (R2) | Ranking R1 | Ranking R2 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBB− ME+ | HBB− ME− | HBB+ME+ | HBB+ME− | HBB+ME+DR+ | HBB+ME− DR+ | Mean score* | HBB− ME+ | HBB− ME− | HBB+ME+ | HBB+ME− | HBB+ ME+DR+ |
HBB+ME− DR+ | Mean score* | |||
| IQ parameter | DWI geometric distortion | |||||||||||||||
| HBB−/ME+/DR− | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 4.2 | x | > 0.05 | > 0.05 | 0.022 | > 0.05 | 0.017 | 4.6 | 2 | 2 |
| HBB−/ME−/DR− | x | x | 0.011 | > 0.05 | > 0.05 | > 0.05 | 3.5 | x | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 4.1 | 6 | 4 |
| HBB+/ME+/DR− | x | x | x | 0.016 | > 0.05 | > 0.05 | 4.3 | x | x | x | 0.004 | > 0.05 | 0.003 | 4.7 | 1 | 1 |
| HBB+/ME−/DR− | x | x | x | x | > 0.05 | > 0.05 | 3.6 | x | x | x | x | > 0.05 | > 0.05 | 4.0 | 5 | 5 |
| HBB+/ME+/DR+ | x | x | x | x | x | > 0.05 | 3.8 | x | x | x | x | x | > 0.05 | 4.3 | 3 | 3 |
| HBB+/ME−/DR+ | x | x | x | x | x | x | 3.8 | x | x | x | x | x | x | 4.0 | 5 | 5 |
| IQ parameter | DWI image quality | |||||||||||||||
| HBB−/ME+/DR− | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 4.0 | x | > 0.05 | > 0.05 | 0.009 | > 0.05 | > 0.05 | 3.8 | 2 | 1 |
| HBB−/ME−/DR− | x | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 3.5 | x | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 3.2 | 4 | 4 |
| HBB+/ME+/DR− | x | x | x | 0.01 | > 0.05 | > 0.05 | 4.1 | x | x | x | > 0.05 | > 0.05 | > 0.05 | 3.7 | 1 | 2 |
| HBB+/ME−/DR− | x | x | x | x | > 0.05 | > 0.05 | 3.5 | x | x | x | x | > 0.05 | > 0.05 | 3.0 | 4 | 6 |
| HBB+/ME+/DR+ | x | x | x | x | x | > 0.05 | 3.8 | x | x | x | x | x | > 0.05 | 3.5 | 3 | 3 |
| HBB+/ME−/DR+ | x | x | x | x | x | x | 3.8 | x | x | x | x | x | x | 3.1 | 3 | 5 |
| IQ parameter | Presence Stool/Gas | |||||||||||||||
| HBB−/ME+/DR− | x | 0.001 | > 0.05 | < 0.001 | 0.02 | 0.18 | 1.5 | x | 0.032 | > 0.05 | < 0.001 | > 0.05 | 0.001 | 1.8 | 2 | 1 |
| HBB−/ME−/DR− | x | x | < 0.001 | > 0.05 | > 0.05 | > 0.05 | 2.3 | x | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 2.4 | 5 | 3 |
| HBB+/ME+/DR− | x | x | x | < 0.001 | > 0.05 | 0.012 | 1.4 | x | x | x | < 0.001 | > 0.05 | 0.007 | 1.9 | 1 | 2 |
| HBB+/ME−/DR− | x | x | x | x | 0.003 | > 0.05 | 2.4 | x | x | x | x | < 0.001 | > 0.05 | 2.7 | 6 | 5 |
| HBB+/ME+/DR+ | x | x | x | x | x | > 0.05 | 1.6 | x | x | x | x | x | 0.007 | 1.9 | 3 | 2 |
| HBB+/ME−/DR+ | x | x | x | x | x | x | 2.1 | x | x | x | x | x | x | 2.6 | 4 | 4 |
| IQ parameter | Whole MRI image quality | |||||||||||||||
| HBB−/ME+/DR− | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 4.0 | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 3.5 | 2 | 1 |
| HBB−/ME−/DR− | x | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 3.6 | x | x | > 0.05 | > 0.05 | > 0.05 | > 0.05 | 3.1 | 4 | 4 |
| HBB+/ME+/DR− | x | x | x | 0.007 | > 0.05 | > 0.05 | 4.2 | x | x | x | > 0.05 | > 0.05 | > 0.05 | 3.3 | 1 | 2 |
| HBB+/ME−/DR− | x | x | x | x | > 0.05 | > 0.05 | 3.5 | x | x | x | x | > 0.05 | > 0.05 | 3.0 | 5 | 5 |
| HBB+/ME+/DR+ | x | x | x | x | x | > 0.05 | 3.8 | x | x | x | x | x | > 0.05 | 3.3 | 3 | 2 |
| HBB+/ME−/DR+ | x | x | x | x | x | x | 3.8 | x | x | x | x | x | x | 3.2 | 3 | 3 |
HBB Hyoscine N-butylbromide, ME Preparatory Microenema, DR dietary restrictions
Statistically significant results between groups (p < 0.05) are highlighted in bold
*Mean Score for DWI Geometric Distortion, DWI Image Quality and Whole MRI Image Quality: 1 best, …, 5 worst
Mean Score for Presence Stool/Gas: 1…high amount of stool, …, 3 no stool
†Rank for DWI Geometric Distortion, DWI Image Quality and Whole MRI Image Quality: 1 best, …, 6 worst
Rank for Presence Stool/Gas: 1…worst, …, 6 best