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. 2021 Jun 1;12(14):2104–2112. doi: 10.1111/1759-7714.14043

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© 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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SGMS1‐AS1 is downregulated in LUAD and correlated to good prognosis for patients. (a) The GEPIA and ENCORI databases illustrate the expression of SGMS1‐AS1 is abnormal in multiple cancers and lower in LUAD tissue compared to normal tissue. (b) The overall survival rate of LUAD patients with a low level of SGMS1‐AS1 is poor according to the ENCORI website. (c) Quantitative reverse transcription PCR (qRT‐PCR) was conducted to compare the expression level of SGMS1‐AS1 between LUAD and para‐carcinoma tissues of 18 patients. (d) The qRT‐PCR revealed that the mRNA level of SGMS1‐AS1 in LUAD cell lines (A549, H1975, and PC9) was consistently lower than that in normal cell lines (HBE)