FIGURE 5.

MYLIP is the target of miR‐106a‐5p and is regulated by SGMS1‐AS1. (a) The ENCORI website predicted that MYLIP is the direct target of miR‐106a‐5p. (b) Luciferase reporter assay showed that miR‐106a‐5p mimic suppressed the level of MYLIP‐WT ability but not MYLIP‐MUT ability. (c) Inhibiting miR‐106a‐5p depressed the expression level of MYLIP. (d) The ENCORI database demonstrated that MYLIP is positively correlated with SGMS1‐AS1. (e) Decreasing SGMS1‐AS1 could downregulate the mRNA level of MYLIP in A549. (f, g) The GEPIA database showed that MYLIP expression was lower in LUAD tissue than in normal tissue and a high level of MYLIP had an obvious relationship with poor prognosis of patients