Table 2.

Univariate and multivariate analysis between clinicopathological characteristics for LCSS of all patients.

	Univariate analysis		Multivariate analysis
Variables	HR (95% CI)	P-value	HR (95% CI)	P-value
Age	1.274 (1.251–1.299)	<0.001	1.088 (1.067–1.109)	<0.001
Gender	0.813 (0.798–0.828)	<0.001	0.819 (0.803–0.835)	<0.001
Histology	1.159 (1.146–1.172)	<0.001	1.102 (1.090–1.114)	<0.001
Grade	1.004 (0.997–1.011)	0.277	–	–
Radiation	0.856 (0.840–0.872)	<0.001	0.977 (0.958–0.996)	0.016
Chemotherapy	0.384 (0.377–0.391)	<0.001	0.381 (0.373–0.388)	<0.001
T stage	1.073 (1.064–1.083)	<0.001	1.055 (1.045–1.065)	<0.001
N stage	1.075 (1.066–1.083)	<0.001	1.101 (1.092–1.110)	<0.001
Metastasis site	1.047 (1.040–1.053)	<0.001	1.036 (1.030–1.043)	<0.001
Primary surgery	0.449 (0.421–0.479)	<0.001	0.658 (0.637–0.680)	<0.001