Table 4.

Univariate and multivariate analysis of clinicopathological characteristics for LCSS of the surgical patients.

	Univariate analysis		Multivariate analysis
Variables	HR (95% CI)	P-value	HR (95% CI)	P-value
Age	1.330 (1.171–1.510)	<0.001	1.176 (1.032–1.341)	0.015
Gender	0.653 (0.574–0.742)	<0.001	0.652 (0.571–0.744)	<0.001
Histology	1.027 (0.961–1.098)	0.426	–	–
Grade	1.072 (1.013–1.134)	0.015	1.112 (1.049–1.179)	<0.001
Radiation	1.014 (0.893–1.151)	0.836	–	–
Chemotherapy	0.650 (0.572–0.738)	<0.001	0.568 (0.496–0.650)	<0.001
T stage	1.150 (1.082–1.222)	<0.001	1.124 (1.055–1.198)	<0.001
N stage	1.273 (1.207–1.341)	<0.001	1.242 (1.178–1.309)	<0.001
Metastasis site	1.086 (1.035–1.139)	0.001	1.001 (0.950–1.055)	0.973
Surgery approach	0.592 (0.524–0.668)	<0.001	0.606 (0.533–0.689)	<0.001