Table 5.

Univariate and multivariate analysis of clinicopathological characteristics for OS of the surgical patients.

	Univariate analysis		Multivariate analysis
Variables	HR (95% CI)	P-value	HR (95% CI)	P-value
Age	1.363 (1.206–1.542)	<0.001	1.206 (1.063–1.369)	0.004
Gender	0.647 (0.572–0.733)	<0.001	0.643 (0.566–0.730)	<0.001
Histology	1.025 (0.961–1.092)	0.458	–	–
Grade	1.077 (1.020–1.137)	0.008	1.116 (1.055–1.181)	<0.001
Radiation	1.014 (0.897–1.146)	0.829	–	–
Chemotherapy	0.628 (0.555–0.710)	<0.001	0.552 (0.484–0.629)	<0.001
T stage	1.140 (1.075–1.208)	<0.001	1.120 (1.053–1.191)	<0.001
N stage	1.252 (1.190–1.317)	<0.001	1.225 (1.164–1.289)	<0.001
Metastasis site	1.083 (1.034–1.134)	0.001	1.001 (0.952–1.054)	0.959
Surgery approach	0.602 (0.535–0.676)	<0.001	0.612 (0.540–0.693)	<0.001