Table 2.
Factors associated with favorable outcome.
| Univariable | Multivariable | ||||
|---|---|---|---|---|---|
| Favorable outcome (n = 116) | Unfavorable outcome (n = 68) | p-value | Odds ratio* (95% CI) | p-value | |
| Age, years | 64.2 (± 14.8) | 74.1 (± 9.9) | <0.001 | 0.95 (0.91–0.99) | 0.018 |
| Male | 76 (65.5) | 30 (44.1) | 0.005 | 0.79 (0.30–2.08) | 0.636 |
| Hypertension | 78 (67.2) | 49 (72.1) | 0.514 | ||
| Diabetes | 28 (24.1) | 25 (36.8) | 0.091 | 0.69 (0.24–1.98) | 0.488 |
| Hypercholesterolemia | 28 (24.1) | 22 (32.4) | 0.235 | ||
| Smoking | 44 (37.9) | 11 (16.2) | 0.002 | 3.19 (0.97–10.5) | 0.056 |
| Coronary artery disease | 5 (4.3) | 6 (8.8) | 0.334 | ||
| Atrial fibrillation | 10 (8.6) | 11 (16.2) | 0.150 | 0.45 (0.11–1.88) | 0.275 |
| Initial NIHSS score | 13.0 [8.0; 16.0] | 16.0 [12.0; 20.0] | <0.001 | 0.90 (0.82–0.98) | 0.017 |
| Occlusion site | 0.903 | ||||
| Internal carotid artery | 28 (24.1) | 17 (25.0) | |||
| Middle cerebral artery | 88 (75.9) | 51 (75.0) | |||
| Use of IV tPA | 45 (38.8) | 18 (26.5) | 0.108 | 1.69 (0.62–4.66) | 0.308 |
| Time of onset to puncture, min | 320 [239; 609] | 290 [202; 710] | 0.631 | ||
| Total procedure time, min | 94 [60; 157] | 104 [84; 147] | 0.781 | ||
| Frontline MT modality | 0.024 | ||||
| Stent retriever | 106 (91.4) | 54 (79.4) | Reference | ||
| Contact aspiration | 10 (8.6) | 14 (20.6) | 0.71 (0.15–3.30) | 0.667 | |
| No. of MT passes | 2.2 (± 1.0) | 3.5 (± 2.1) | <0.001 | 0.47 (0.31–0.71) | <0.001 |
| Endovascular modalities | <0.001 | ||||
| MT alone | 7 (6.0) | 17 (25.0) | Reference | ||
| MT-RS | 11 (9.5) | 14 (20.6) | 1.41 (0.07–27.9) | 0.822 | |
| MT-GPI | 55 (47.4) | 29 (42.6) | 3.21 (0.44–23.5) | 0.250 | |
| MT-RS+GPI | 43 (37.1) | 8 (11.8) | 20.4 (1.97–211.4) | 0.012 | |
| Successful recanalization | 113 (97.4) | 55 (80.9) | <0.001 | 8.48 (1.01–71.8) | 0.049 |
| Patent artery on follow-up | 109 (94.0) | 42 (61.8) | <0.001 | 14.1 (2.05–97.4) | 0.007 |
| Postprocedural antithrombotics | <0.001 | ||||
| None | 18 (15.5) | 34 (50.0) | Reference | ||
| Oral antiplatelets immediately after procedure | 8 (6.9) | 6 (8.8) | 1.62 (0.26–9.96) | 0.603 | |
| IV GPI infusion followed by oral antiplatelets | 90 (77.6) | 28 (41.2) | 22.8 (1.09–475.9) | 0.044 | |
IV tPA, intravenous tissue plasminogen activator; MT, mechanical thrombectomy; MT-RS, rescue stenting after mechanical thrombectomy failure; MT-GPI, glycoprotein IIb/IIIa infusion after mechanical thrombectomy failure; MT-RS+GPI, rescue stenting with glycoprotein IIb/IIIa infusion after mechanical thrombectomy failure; IV GPI, intravenous glycoprotein IIb/IIIa inhibitor; NIHSS, National Institutes of Health Stroke Scale.
Values in parentheses represent the standard deviation or the number of patients (%). Brackets represent first and third quartiles.
*
Odds ratio for favorable outcome.