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. 2021 Jul 5;8:676979. doi: 10.3389/fmed.2021.676979

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Copyright © 2021 Lopez-Alvarenga, Martinez, Diaz-Badillo, Morales, Arya, Jenkinson, Curran, Lehman, Blangero, Duggirala, Mummidi and Martinez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Violin plots showing relationship between triglycerides (A) and HDL-C (B) with BMI categories after adjusting for age, sex, cohort, and T2D status. The presence of diabetes was associated with higher triglyceride concentration [b = 28.2 (se 12.3), p = 0.02] and lower HDL-C [b = −3.5 (se 0.9) p < 0.001]. The HDL-C showed interaction for VACC [b = 2.2 (se 1.1) p = 0.042]. HHANES: The Hispanic component of NHANES 2018 cohort; SAMAFS, San Antonio Mexican American Family Studies; VACC, Valley AIDS Council Cohort. NW, normal weight; OW, overweight; OB-C1, obesity-category 1; OB-C2, obesity-category 2; and OB-C3, obesity category 3. The continuous horizontal line represents the mean value without adjustment.