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. 2021 Jul 13;6(4):100214. doi: 10.1016/j.esmoop.2021.100214

Table 1.

IDH1-directed vaccines in clinical trials

Name of the compound Mechanism of action Phase of clinical trial development Company
IDH1-vac Activation of IDH1R132H-specific T cells I German Cancer Research Center, Heidelberg University
PEPIDH1M Activation of IDH1R132H-specific T cells I Duke University
IDH1R132H-DC vaccine Activation of IDH1R132H-specific T cells I Beijing Tiantan Hospital

IDH, isocitrate dehydrogenase.