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. 2021 Jul 5;9:699771. doi: 10.3389/fcell.2021.699771

FIGURE 5.

FIGURE 5

Outline of an optical tweezer set-up. (A) In the helping force mode, DNA is labeled upstream of RNAP leading to increased distance between the two beads and decreased force generation. (B) In the assisting force mode, DNA is labeled downstream of RNAP resulting in shortened distance between the two beads and increased force generation.