Table 3.
Results of the meta-regression analysis of DWI for discriminating benign and malignant IPMN.
| Covariates | Subgroup | Studies (n) | Meta-analytic summary estimates | |||
|---|---|---|---|---|---|---|
| Sensitivity | P | Specificity | p | |||
| (95% CI) | ||||||
| (95% CI) | ||||||
| Study enrollment | Consecutive enrollment | 1 | 0.79 (0.59–0.99) | 0.82 | 0.82 (0.54–1.00) | 0.36 |
| NA | 5 | 0.73 (0.64–0.82) | 0.95 (0.88–1.00) | |||
| Reader experience | Available | 4 | 0.73 (0.62–0.83) | 0.13 | 0.95 (0.85–1.00) | 0.32 |
| NA | 2 | 0.78 (0.63–0.92) | 0.95 (0.83–1.00) | |||
| Number of readers | n = 1 | 4 | 0.78 (0.70–0.85) | 0.81 | 0.86 (0.81–0.92) | 0.07 |
| n = 2 | 2 | 0.66 (0.49–0.82) | 1.00 (1.00–1.00) | |||
| Magnetic strength | 1.5T | 3 | 0.77 (0.65–0.90) | 0.11 | 0.97 (0.91–1.00) | 0.71 |
| 3T | 3 | 0.72 (0.60–0.85) | 0.91 (0.79–1.00) | |||
| Max value of b value | ≥1,000 | 3 | 0.77 (0.67–0.87) | 0.05 | 0.90 (0.78–1.00) | 0.08 |
| <1,000 | 3 | 0.71 (0.58–0.84) | 0.97 (0.91–1.00) | |||
| Thickness of DWI | 5 mm | 2 | 0.78 (0.68–0.88) | 0.02* | 0.85 (0.79–0.91) | 0.19 |
| 7 mm | 4 | 0.72 (0.62–0.82) | 0.97 (0.94–1.00) | |||
| DWI parameter | quantitative DWI | 3 | 0.72 (0.60–0.84) | 0.21 | 0.97 (0.92–1.00) | 0.01* |
| qualitative DWI | 3 | 0.77 (0.68–0.85) | 0.86 (0.80–0.92) | |||
*Denotes a statistical significance.
DWI, diffusion-weighted imaging; NA, not available.