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. 2021 Jun 25;12:200221. doi: 10.1016/j.tvr.2021.200221

Fig. 2.

Fig. 2

Number of variants, nonsynonymous and synonymous variations in the different HPV genes. A) Heat map with yellow-orange-purple gradient colour-coding representing mean number of variants per sample in HPV16 and HPV18 genomic regions. Number of variants is normalised by the gene length and stratified by the diagnostic category. B) Heat map with blue-white-red gradient colour-coding representing the ratio of non-synonymous to synonymous substitutions (dN/dS) in HPV16 and HPV18 genomic regions across the different diagnostic categories.