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. 2021 Jun 25;12:200221. doi: 10.1016/j.tvr.2021.200221

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© 2021 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 4 — Chromosomal integration sites and HPV break points in HPV16 and HPV18 positive samples. A) Number of integration sites in samples with observed integration. Each spot in the plot indicates one sample. Total number of samples with integration is specified for each diagnostic category on x-axis. Vertical lines indicate the mean number of integration sites. B) Break points in HPV genes. C) Integration sites in human chromosomes compared to expected number of break points assuming random viral genome integration.