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. 2021 Jul 5;9:676142. doi: 10.3389/fcell.2021.676142

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Copyright © 2021 Wang, Chen, Ying, Ma, Shen, Li, Wang, Lin, Liu, Zheng and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association of PD-L1 with ferroptosis regulators and the differential infiltration level of tumor immune cells in two clear cell renal cell carcinoma (ccRCC) subtypes. (A,B) The expression level of PD-L1 in ccRCC/normal group (A) and cluster 1/2 subtype (B) in ccRCC. (C) The correlation of PD-L1 with ferroptosis regulators in the TCGA-KIRC cohort. (D) The infiltrating levels of various immune cell types in two subtypes in the TCGA-KIRC cohort. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.