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. 2021 Jul 5;9:676142. doi: 10.3389/fcell.2021.676142

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Copyright © 2021 Wang, Chen, Ying, Ma, Shen, Li, Wang, Lin, Liu, Zheng and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation analysis of CARS expression with PD-L1 and infiltrating immune cells in clear cell renal cell carcinoma (ccRCC). (A,B) The enriched Gene Ontology (A) and Kyoto Encyclopedia of Genes and Genomes signaling pathways (B) analysis of highly expressed CARS in ccRCC. (C) Spearman correlation analysis of CARS expression and PD-L1 expression in ccRCC. (D) The infiltrating levels of immune cells in high and low CARS expression groups in ccRCC patients. (E) The heat map visualized the percentage abundance of tumor-infiltrating immune cells in each sample. *p < 0.05, **p < 0.01, and ***p < 0.001.