Table 3.

Values of the seroconversion rate (SCR), geometric mean titers (GMTS), GMT increase (GMTi), and seroprotection rate (SPR) by HI against types and subtypes of influenza viruses after seasonal flu vaccination, by groups of age and gender analyzed.

Strain/Subtype	Pre-vaccine	Vaccinated cohorts				Significance (p-value)
		Men 15–64	Women 15–64	Men ≥ 65	Women ≥65	Men vs. Women 15–64	Men vs. Women ≥65
A(H1N1)	SCR (%)	27.9	37.4	30.2	40.6	0.158	0.005*
	GMTi	2.2	3.2	2.3	2.9	0.123	0.055
	GMTs (CI95%)	80.5 (62.0–104.7)	99.0 (75.1–130.5)	58.0 (50.6–66.5)	66.5 (58.9–75.2)	0.306	0.117
	SPR (%)	77.9	81.3	68.8	74.5	0.554	0.147
A(H1N1pdm09)	SCR (%)	48.2	46.7	42.0	52.4	0.789	0.001*
	GMTi	3.6	3.6	3.0	3.7	0.579	0.000*
	GMTs (CI95%)	268.8 (227.3–318.0)	327.4 (283.3–378.4)	163.2 (146.8–181.3)	182.7 (166.2–200.8)	0.184	0.077
	SPR (%)	95.6	96.2	89.9	93.7	0.909	0.542
A(H3N2)	SCR (%)	39.6	45.3	44.7	47.1	0.250	0.399
	GMTi	3.4	3.5	3.2	3.3	0.983	0.175
	GMTs (CI95%)	204.5 (169.4–246.8)	232.8 (195.7–276.9)	233.7 (210.1–260.0)	247.5 (226.0–271.2)	0.667	0.286
	SPR (%)	92.0	95.0	93.3	94.9	0.402	0.865
B/Yamagata	SCR (%)	24.6	24.4	21.0	24.6	0.961	0.092
lineage	GMTi	2.0	2.1	1.7	1.9	0.987	0.108
	GMTs (CI95%)	246.2 (211.5–286.6)	247.2 (215.8–283.2)	205.1 (187.4–224.3)	227.7 (210.5–246.4)	0.983	0.158
	SPR (%)	95.9	96.8	93.9	95.5	0.805	0.980
B/Victoria	SCR (%)	26.6	28.3	18.9	23.2	0.664	0.039*
lineage	GMTi	2.3	2.3	1.9	1.9	0.317	0.243
	GMTs (CI95%)	183.1 (154.8–216.7)	146.5 (124.7–172.0)	193.1 (176.3–211.6)	187.5 (172.8–203.4)	0.053	0.557
	SPR (%)	95.9	96.8	93.9	95.5	0.805	0.649

P-values of the comparison between both genders for each age group.

Significant differences (p<0.05) are marked with *.