The fabrication process of several kinds of modules. (A) Six fabrication methods of cell spheroids modules[34], including (A1) suspension cell culture, (A2) hanging drop, (A3) microwell, (A4) microwell array from micropatterned agarose wells (Republished with permission from Rivron NC, Vrij EJ, Rouwkema J, et al., Proc Natl Acad Sci, 2012, 109:6886–91.[35]), and finally, (A5) microchannel forming (Reproduced from ref. 36 with permission from The Royal Society of Chemistry). (B) Fabrication process of fiber module by microchannels[30]. (C) Fabrication process of microplates and rings by (C1) photolithography (Republished with permission from Teshima T, Onoe H, Kuribayashiashiashias K, et al., Small, © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim[38]). and (C2) dielectrophoresis (from ref.[39] licensed under Creative Commons Creative Commons Attribution License). (D) Layer-by-layer fabrication process of cell sheets[44].