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. 2021 Jul 5;8:665222. doi: 10.3389/fmolb.2021.665222

FIGURE 3.

FIGURE 3

Association between the m6A RNA methylation regulators and clinicopathological and prognostic features of melanoma patients. (A) consensus clustering model with cumulation distribution function (CDF) for K = 2–9 (K means cluster count). (B) Relative change in area under the CDF curve for K = 2–9. (C) The Cancer G enome Atlas (TCGA) melanoma cohort was classified into three clusters with K = 2. (D) Principal component analysis of the total RNAexpression profile of cluster 1 (red), cluster 2 (blue). (E) The correlation of the two cluster with clinicopathologic features was visualized by heatmap. p < 0.05 (“*”).