Table 2.
Summary of main effects and interactions of predictors on WMH volume and location.
| WMH Volume | Main Effects | Location Interaction | ||
|---|---|---|---|---|
| Predictors | F-value | p-value | F-value | p-value |
| Age | 0.658 | 0.420 | 0.302 | 0.584 |
| Sex | 1.161 | 0.285 | 2.250 | 0.138 |
| ICV | 3.032 | 0.086 | 0.103 | 0.750 |
| CBF | 3.530 | 0.065 | 0.029 | 0.866 |
| QSM | 5.107 | 0.027* | 6.208 | 0.015* |
| RD | 13.516 | <0.001* | 0.053 | 0.819 |
| CBF × QSM | 0.573 | 0.452 | 0.689 | 0.410 |
| QSM × RD | 0.026 | 0.874 | 0.241 | 0.625 |
| CBF × RD | 0.018 | 0.894 | 0.127 | 0.723 |
The F- and p-values for the main effects of predictors on total WMH volume are on the left, with the interaction effects of WMH location on the right. QSM and RD had robust main effects, while CBF had a marginally significant main effect on total WMH volume. Only QSM interacted with WMH location.
*
p < 0.05.