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. 2021 Jul 5;11:698594. doi: 10.3389/fonc.2021.698594

Table 1.

Clinical characteristics of patients in the short-, intermediate-, and long-wait groups.

Varible All patients (n = 316) SWT (days) Short <31 (n = 173) Intermidiate [31,90] (n = 69) Long >90 (n = 74) P
Age (yr) 69 (61-75) 69 (59-75) 69 (68-79) 68 (61-75) 0.376
Sex 0.352
 Male 205 110 (34.8%) 42 (13.3%) 53 (16.8%)
 Female 111 63 (19.9%) 27 (8.5%) 21 (6.7%)
Smoke 0.511
 Yes 70 34 (10.8%) 17 (5.4%) 19 (6.1%)
 No 245 138 (43.7%) 52 (16.5%) 55 (17.5%)
ECOG performance status 0.986
 0 199 109 (34.6%) 43 (13.7%) 47 (14.9%)
 1 116 63 (19.9%) 26 (8.3%) 27 (8.6%)
Median Body mass index (kg/m2) 22.6 (20.1-25.2) 22.5 (20.4-24.7) 22.4 (20.1-24.9) 22.8 (19.7-25.3) 0.120
Haematuria 0.000
  (+) 223 95 (30.1%) 58 (18.4%) 70 (22.2%)
  (-) 91 77 (24.4%) 11 (3.5%) 3 (0.9%)
Hydronephrosis 0.429
  (+) 158 92 (29.1%) 33 (10.4%) 33 (10.4%)
  (-) 158 81 (25.6%) 36 (11.4%) 41 (13.1%)
Tumor location 0.032
 Renal pelvis 173 84 (26.6%) 40 (12.7%) 49 (15.5%)
 Ureter 143 89 (28.2%) 29 (9.2%) 25 (7.8%)
Tumor grade 0.311
 High 234 132 (41.8%) 52 (16.5%) 50 (15.8%)
 Low 81 40 (12.8%) 17 (5.4%) 24 (7.7%)
Tumor size 3.5 (2.5-5) 3.5 (2.5-5.0) 3.5 (2.5-4.8) 3.0 (2.0-5.0) 0.949
Amount of lesions 0.137
 Single 270 144 (45.6%) 64 (20.1%) 62 (19.6%)
 Mutiple 45 29 (9.2%) 5 (1.6%) 12 (3.9%)
pT stage 0.310
 ≤pT1 87 51 (16.1%) 14 (4.4%) 22 (7.0%)
 pT2 111 54 (17.0%) 30 (9.5%) 27 (8.4%)
 pT3 97 57 (18.0%) 17 (5.3%) 23 (7.3%)
 pT4 21 11 (6.6%) 8 (3.4%) 2 (0.6%)
Lymph node involvement 0.706
 pN0 282 151 (47.8%) 64 (20.3%) 67 (21.1%)
 pN+ 34 22 (7.0%) 5 (1.6%) 7 (2.2%)
LND 0.861
 Yes 81 46 (14.6%) 16 (5.1%) 19 (6.0%)
 No 235 127 (40.2%) 53 (16.8%) 55 (17.4%)
Surgical approch 0.352
 Open 67 37 (11.7%) 18 (5.7%) 12 (3.9%)
 Laparoscopy 249 136 (43.0%) 51 (16.1%) 62 (19.6)
Surgical margin 1.000
 Positive 0 0 ( 0.0%) 0 (0.0%) 0 (0.0%)
 Negative 316 173 (54.7%) 69 (21.8%) 74 (23.4%)
Tumor necrosis 0.789
 Yes 87 48 (15.2%) 17 (5.4%) 22 (7.0%)
 No 229 125 (39.6%) 52 (16.5%) 52 (16.5%)
Infiltrative tumor 0.313
Architecture
 Yes 229 122 (38.6%) 55 (17.4%) 52 (16.5%)
 No 87 51 (16.1%) 14 (4.4%) 22 (7.0%)
lymphovascular invasion 0.128
 Yes 38 26 (8.2%0 4 (1.3%) 8 (2.5%)
 No 278 147 (46.5%) 65 (16.5%) 66 (20.9%)
Complicated with bladder cancer
 Yes 20 10 (3.2%) 5 (1.6%) 5 (1.6%) 0.901
 No 296 163 (51.6%) 64 (20.3%) 69 (21.8%)

ECOG, Eastern Cooperative Oncology Group.