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. Author manuscript; available in PMC: 2021 Dec 17.
Published in final edited form as: Nat Metab. 2021 Jun 17;3(6):762–773. doi: 10.1038/s42255-021-00410-x

Extended Data Fig. 3. The H6D does not induce a diabetic phenotype.

Extended Data Fig. 3

a,b, Scatter plots of fasting blood glucose levels (a) and HbA1c levels (b) from mice on L6D and H6D for 8 weeks. Mice on normal chow (NC) and 16-week-old db/db mice served as negative and positive controls, respectively (NC, n=5; L6D, n=5; H6D, n=5; db/db, n=5). Dotted lines in each figure represent established cut-offs for type 2 diabetes. ****P<0.0001 (db/db vs NC). c,d, Weekly monitoring of body weights (c) and food intake (d) for both male and female mice on either L6D or H6D. Data are mean ± SEM. Error bars for some data points are within the size of the symbol. Statistical test used was one-way ANOVA with Tukey’s post-hoc test (a,b).