Figure 1.

The analyses and indicators employed in our research. In clinical correlation section, differential AhR expression analyses were performed between different tissues (tumor versus normal), ages (<=65 versus >65), genders (male versus female), stages (stage I+II versus stage III+IV). Survival correlation analyses were based on univariate Cox regression analysis. In immune mechanism section, relevant signaling pathways were explored by GSEA based on the AhR expression. In immunotherapeutic response section, Wilcoxon test was performed based on the AhR expression of non-responder and responder groups.