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. 2021 Jul 19;14:95. doi: 10.1186/s13048-021-00846-5

Table 2.

Mean number of follicles after in vitro organotypic culture of cryopreserved whole ovaries in presence of pharmacological inhibitors

CT LY Ra
24 h
Primordial 20.53 ± 1.906 21.22 ± 1.584b 26.81 ± 1.516a
Primary 16.61 ± 3.265 8.993 ± 2.302 7.72 ± 1.348
Secondary or more 42.37 ± 2.56 48.65 ± 3.192b 38.73 ± 2.397

Ovaries from Nu/Nu mice, 4-weeks old, n = 5 ovaries per group

Results are expressed in percentage of primordial, primary and secondary or more mature follicles relative to the total number of follicles present in one ovarian slide. Mean ± SEM

CT Control, LY LY294002, Ra Rapamycin

adifferent from CT, bdifferent from Ra