Table 2.

Association between HE4 levels ^a and tomographic response (n = 53)

	Univariable			Multivariableb
HE4	Estimated	CI 95%	p	Estimated	CI 95%	p
Basal	-0244	-0.689, 0.151	0.357	-0.262	-0.832, 0.308	0.367
To the first cycle	0.444	-0-249, 0.561	0.119	0.524	-0.077, 1.125	0.088
To the second cycle	0.676	0.061, 1.081	0.054	0.752	0.028, 1.475	0.044
To the third cycle	0.766	0.175, 1.181	0.042	0.843	0.068, 1.617	0.033
All values	0.241	0.012, 0.352	0.038	0.268	0.030, 0.505	0.027

CI confidence interval

^a Transformed by decimal logarithm. Measurements of all cycles and basal values were included

^b Adjusted for age at diagnosis, baseline ECOG, smoking the histological subtype and FIGO stage

Those p values with statistical significance (less than 0.05) are marked in bold