Table 3.

Association between tomographic response and the difference (delta) between HE4^alevels (n=53)

	Univariate			Multivariateb
HE4	Est	CI 95%	p	Est	CI 95%	p
Between basal and first cycle	0.182	0.033, 0.330	0.017	0.194	0.019, 0.368	0.030
Between basal and second cycle	0.116	-0.013, 0.245	0.080	0.128	-0.013, 0.269	0.077
Between basal and third cycle	0.090	0.060, 0.240	0.244	0.108	-0.058, 0.274	0.203
Between first and second cycle	0.069	-0.125, 0.263	0.485	0.203	-0.092, 0.498	0.179

CI confidence interval

^a Transformed by decimal logarithm

^b Adjusted for age at diagnosis, basal ECOG, smoking, histological subtype and FIGO stage

Those p values with statistical significance (less than 0.05) are marked in bold