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. 2021 Jul 19;16:319. doi: 10.1186/s13023-021-01950-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — The clinical features in patients with LAMA2-related muscular dystrophy. a Kaplan–Meier survival analysis in patients with LAMA2-related muscular dystrophy. b Comparison of achievemet of head control in patients with LAMA2-related muscular dystrophy. c Comparison of achievemet of sitting in patients with LAMA2-related muscular dystrophy. d Comparison of achievemet of ambulation in patients with LAMA2-related muscular dystrophy. e Joint contractures in patients with LAMA2-CMD in different ages. f Recurrent respiratory infection in patients with LAMA2-CMD in different ages. LAMA2-CMD LAMA2-related congenital muscular dystrophy, LGMDR23 autosomal recessive limb-girdle muscular dystrophy-23, RRI recurrent respiratory infection