Table 1.
Background and diagnostic factors in all 277 cases and their relationship to patient prognoses
| Factors | Patient numbers | Median PFS (months) | P values | Median OS (months) | P values | ||
|---|---|---|---|---|---|---|---|
| All cases | 277 | 8.7 | 16.6 | ||||
| Age | Median (percentile) | 66 | (57–74) | ||||
| 66 or more | 149 | (53.8%) | 8.2 | 0.334 | 13.8 | 0.006 | |
| 65 or less | 128 | (46.2%) | 9.4 | 19.3 | |||
| Sex | Men (%) | 165 | (59.6%) | 8.4 | 0.281 | 16.6 | 0.966 |
| Women | 112 | (40.4%) | 8.7 | 15.7 | |||
| Main Location | Frontal | 103 | (37.2%) | 8.6 | 0.395 | 16.2 | 0.179 |
| Temporal | 93 | (33.6%) | 8.3 | 15.1 | |||
| Parieto-Occipital | 40 | (14.4%) | 9.2 | 24.8 | |||
| Others | 41 | (14.8%) | 9.8 | 15.7 | |||
| Side | Right | 132 | (47.7%) | 9.8 | 0.030 | 19.1 | 0.013 |
| Left | 118 | (42.6%) | 8.2 | 15.9 | |||
| Others | 27 | (9.7%) | 5.1 | 11.0 | |||
| KPS | Median (percentile) | 70 | (60–80) | ||||
| 70 or more | 190 | (68.6%) | 9.2 | 0.190 | 19.7 | 0.006 | |
| 60 or less | 87 | (31.4%) | 8.6 | 11.2 | |||
| EOR | Non-biopsy | 200 | (72.2%) | 9.5 | 19.7 | ||
| GTR (100% of EOR) | 91 | (32.9%) | 11.3 | 0.000 | 26.5 | 0.000 | |
| STR | 58 | (20.9%) | 9.2 | 21.7 | |||
| PR | 51 | (18.4%) | 5.3 | 11.1 | |||
| Biopsy | 77 | (27.8%) | 7.1 | 9.7 | |||
| 5-ALA | Strong | 190 | (68.6%) | 9.1 | 0.096 | 16.8 | 0.300 |
| Vague | 31 | (11.2%) | 6.7 | 14.4 | |||
| Positive | 11 | (4.0%) | 11.5 | 18.0 | |||
| Negative | 8 | (2.9%) | 10.3 | 13.7 | |||
| Not used/Unknown | 37 | (13.4%) | 4.9 | 16.7 | |||
|
Intraoperative MRI |
Yes (for removal) | 82 | (29.6%) | 11.2 | 0.009 | 21.7 | 0.000 |
| Yes (for biopsy) | 12 | (4.3%) | 6.4 | 8.2 | |||
| Not used | 183 | (66.1%) | 8.1 | 14.7 |