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. 2021 Jul 5;12:667029. doi: 10.3389/fendo.2021.667029

Table 1.

Clinical characteristics and risk factors.

Characteristics Total (N = 161)
PP (N = 84) Control(N = 77) p-value
Age (years) 7.9 ± 1.8 10.0 ± 2.1 <0.001
BMI-SDS 1 ± 1.4 0.5 ± 1.2 <0.05
Thelarche (years) 7.2 ± 1.8 9.4 ± 2.2 <0.001
Pubarche (years) 7.3 ± 1.7 9.1 ± 2.7 <0.001
Menarche (years) 12.8 ± 1.3 10.8 ± 0.7 <0.005
Mother’s menarche (years) 12.2 ± 1.6 11.7 ± 1.1 NS (0.128)
EBF duration (years) 0.3 ± 0.2 0.4 ± 0.3 <0.05
EBF >6 months (yes, %) 28 (33%) 38 (49%) 0.05 (OR: 0.5; IC 95%:0.3–0.9)
Use of soy-based formulas (yes, %) 23 (28%) 7 (9%) <0.05 (OR: 3.8; IC 95%: 1.5–9)

PP, precocious puberty; BMI-SDS, body mass index standard deviation score; EBF, exclusive breastfeeding; NS, not significant.