Skip to main content
. 2021 Jul 5;12:712030. doi: 10.3389/fmicb.2021.712030

FIGURE 1.

FIGURE 1

The N. maritimus 3-hydroxypropionate/4-hydroxybutyrate cycle (A) and the I. hospitalis dicarboxylate/4-hydroxybutyrate cycle (B) adapted from Berg et al. (2010b) and Könneke et al. (2014). Enzymes: 1, acetyl-CoA carboxylase; 2, malonyl-CoA reductase; 3, malonic semialdehyde reductase; 4, 3-hydroxypropionyl-CoA synthetase; 5, 3-hydroxypropionyl-CoA dehydratase; 6, acryloyl-CoA reductase; 7, propionyl-CoA carboxylase; 8, methylmalonyl-CoA epimerase; 9, methylmalonyl-CoA isomerase; 10, succinyl-CoA reductase; 11, succinic semialdehyde reductase; 12, 4-hydroxybutyryl-CoA synthetase; 13, 4-hydroxybutyryl-CoA dehydratase; 14, crotonyl-CoA hydratase; 15, (S)-3-hydroxybutyryl-CoA dehydrogenase; 16, acetoacetyl-CoA β-ketothiolase; 17, pyruvate synthase; 18, PEP synthase; 19, PEP carboxylase; 20, malate dehydrogenase; 21, fumarate hydratase; 22, fumarate reductase; 23, succinyl-CoA synthetase. CoASH, coenzyme A; PEP, phosphoenolpyruvate; Fd, ferredoxin; MV, methyl viologen.