FIGURE 6.

Staquorsin is effective in controlling S. aureus skin infection. (A) Monitoring the weights of the mice throughout the course of the infection. The weights of mice were determined every 24 h and they are presented as percentages of the weights at day 0. The data presented is the average of the readings of the mice in each group; treated with the vehicle (closed circles) and staquorsin (open squares), and the error bars represent the standard deviation. Statistical analyses were performed by applying an unpaired t test for each pair representing the readings at the indicated time point. (B) Photographs of a representative mouse of each group (treated with vehicle vs staquorsin). The images were taken on day seven post-infection. (C) Box plots of the bacterial loads in the skin lesions of mice infected with S. aureus and treated with either the vehicle or staquorsin. The data is presented as Log₁₀CFU/ml obtained following plating the homogenates of the skin lesions excised from the infected mice. The whiskers span the difference between the minimum and maximum readings; the horizontal bar represents the mean. The “^∗” indicates a p-value ≤ 0.05, and “^∗∗∗” p-value ≤ 0.001.