Table 2.
Properties of candidate hotspot genes in GM11713
| Chrom | Gene | APH Rep. Delay in G2/M | Rep. Timing in S (no APH) | Size | Bru-Seq RPKM |
|---|---|---|---|---|---|
| hChr3 | FHIT | -0.356 | -0.063 | 1.5 Mbp | 0.332 |
| mChr12 | Immp2l | -0.285 | -0.156 | 931 kbp | 0.370 |
| hChr3 | NLGN1 | -0.261 | -0.261 | 888 kbp | 1.743 |
| hChr3 | ZBTB20 | -0.230 | -0.102 | 833 kbp | 4.902 |
| mChr14 | Gpc6 | -0.085 | -0.023 | 1.1 Mbp | 1.472 |
| mChr8 | Wwox | -0.073 | -0.040 | 913 kbp | 0.197 |
| mChr13 | Sugct | -0.060 | -0.019 | 837 kbp | 1.143 |
| hChr3 | ERC2 | -0.030 | 0.017 | 960 kbp | 0.744 |
| mChr14 | Lrmda | -0.025 | 0.085 | 1.0 Mbp | 0.264 |
| mChr1 | Pard3b | 0.006 | 0.054 | 1.0 Mbp | 0.873 |
| correlation coefficient | 0.89 | 0.04 | -0.14 | ||
The table includes all genes with an active GM11713 transcription unit of at least 750 kbp on human (h) and mouse (m) chromosomes. Correlation coefficients are for APH-induced replication delay in G2/M relative to basal replication timing in S, gene size in bp and Bru-seq transcription RPKM. The table is sorted by decreasing replication delay.