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. 2019 Apr 4;75(9):1905–1910. doi: 10.1093/geronb/gbz040

Table 3.

Summary of Mediation Analyses Predicting Falls From Conscientiousness and Neuroticism

Mediating effect Direct effect Total effect
Personality traits MV Estimate 95% CI p Estimate 95% CI p Estimate 95% CI p
Conscientiousness
 Disease burden 0.021 0.012 to 0.030 <.001 0.154 0.087 to 0.222 <.001 0.175 0.107 to 0.143 <.001
 Depression 0.055 0.042 to 0.069 <.001 0.110 0.041 to 0.178 .009 0.165 0.097 to 0.233 <.001
 Cognition 0.005 −0.001 to 0.011 .197 0.170 0.103 to 0.237 <.001 0.175 0.107 to 0.233 <.001
 Physical inactivity 0.015 0.006 to 0.025 .007 0.158 0.091 to 0.226 <.001 0.174 0.106 to 0.241 <.001
 Smoking 0.013 −0.002 to 0.038 .168 0.171 0.104 to 0.238 <.001 0.184 0.115 to 0.253 <.001
 Handgrip strength 0.004 0.000 to 0.009 .140 0.171 0.103 to 0.238 <.001 0.175 0.107 to 0.242 <.001
 All mediators 0.080 0.059 to 0.101 <.001 0.095 0.026 to 0.164 .023 0.175 0.106 to 0.245 <.001
Neuroticism
 Disease burden 0.023 0.015 to 0.031 <.001 0.116 0.060 to 0.171 .001 0.139 0.084 to 0.194 <.001
 Depression 0.089 0.069 to 0.109 <.001 0.044 −0.014 to 0.102 .221 0.133 0.078 to 0.188 <.001
 Cognition 0.003 −0.001 to 0.006 .205 0.137 0.082 to 0.192 <.001 0.140 0.085 to 0.195 <.001
 Physical inactivity 0.010 0.004 to 0.016 .006 0.131 0.076 to 0.186 <.001 0.141 0.086 to 0.196 <.001
 Smoking 0.019 0.004 to 0.034 .035 0.135 0.080 to 0.190 <.001 0.154 0.097 to 0.211 <.001
 Handgrip strength 0.010 0.004 to 0.016 .007 0.129 0.072 to 0.186 <.001 0.141 0.086 to 0.196 <.001
 All mediators 0.121 0.096 to 0.146 <.001 0.024 −0.034 to 0.082 .492 0.146 0.088 to 0.203 <.001

Notes. Conscientiousness scores were reverse-coded for ease of interpreting the direction of effects. MV = mediating variable.