Table 1.
Summary of the training set
| Ligand | InteracDome threshold | Number of binding domains | Number of positives | Number of negatives |
|---|---|---|---|---|
| RNA | 0.5 | 21 | 247 | 43 720 |
| DNA | 0.5 | 33 | 397 | 43 884 |
| Ion | 0.75 | 91 | 351 | 39 630 |
| Peptide | 0.5 | 72 | 436 | 41 105 |
| Small molecule | 0.5 | 132 | 825 | 32 697 |
For each ligand type, we use the specified InteracDome (15) threshold to define binding (i.e., positives). Positions with an InteracDome score of 0 are deemed non-binding (i.e., negative). We list here the number of binding domains, the number of positives and the number of negatives we use in the dSPRINT training.