TABLE 3.
Pooled adjusted mean (SE) of 24-h urine components, by categories of the aMED
| aMED score | P value for trend | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8–9 | ||
| Ca, mg | 190 (10) | 188 (5) | 197 (4) | 200 (4) | 191 (4) | 195 (4) | 196 (4) | 198 (4) | 188 (6) | 0.99 |
| Ox, mg | 31.1 (1.1) | 30.3 (0.6) | 31.4 (0.5) | 32.4 (0.4) | 33.0 (0.4) | 32.8 (0.4) | 33.4 (0.4) | 34.5 (0.5) | 35.7 (0.7) | <0.001 |
| Cit, mg | 626 (29) | 664 (16) | 665 (12) | 686 (11) | 687 (10) | 698 (11) | 710 (11) | 707 (13) | 741 (17) | <0.001 |
| UA, mg | 524 (14) | 516 (8) | 519 (6) | 529 (5) | 526 (5) | 538 (5) | 536 (6) | 533 (6) | 549 (8) | <0.001 |
| Na, mmol | 158 (6) | 151 (3) | 154 (2) | 155 (2) | 152 (2) | 149 (2) | 152 (2) | 152 (3) | 143 (3) | <0.001 |
| K, mmol | 56.4 (2.1) | 57.6 (1.1) | 58.8 (0.8) | 61.4 (0.7) | 62.8 (0.7) | 64.8 (0.7) | 66.6 (0.8) | 68.9 (0.9) | 71.8 (1.2) | <0.001 |
| Mg, mg | 96 (4) | 99 (2) | 104 (2) | 102 (1) | 107 (1) | 109 (1) | 110 (2) | 114 (2) | 114 (2) | <0.001 |
| P, mg | 734 (32) | 674 (17) | 720 (13) | 706 (12) | 732 (11) | 715 (12) | 738 (13) | 754 (15) | 750 (19) | <0.001 |
| pH | 5.90 (0.05) | 5.98 (0.03) | 5.94 (0.02) | 5.99 (0.02) | 5.98 (0.02) | 6.01 (0.02) | 6.06 (0.02) | 6.02 (0.02) | 6.06 (0.03) | <0.001 |
| V, L | 1.55 (0.08) | 1.58 (0.04) | 1.64 (0.03) | 1.69 (0.03) | 1.72 (0.03) | 1.81 (0.03) | 1.85 (0.03) | 1.89 (0.03) | 1.89 (0.05) | <0.001 |
| Creat, mg | 1309 (25) | 1330 (13) | 1315 (10) | 1332 (9) | 1335 (9) | 1339 (9) | 1326 (10) | 1322 (11) | 1345 (15) | 0.33 |
| RSS,1 CaOx | 1.80 (0.14) | 1.70 (0.07) | 1.76 (0.06) | 1.72 (0.05) | 1.63 (0.05) | 1.64 (0.05) | 1.55 (0.05) | 1.61 (0.06) | 1.47 (0.08) | <0.001 |
| SS,2 CaOx | 5.76 (0.55) | 5.77 (0.28) | 5.93 (0.23) | 5.74 (0.21) | 5.63 (0.20) | 5.22 (0.20) | 5.35 (0.22) | 5.33 (0.25) | 5.61 (0.31) | 0.007 |
| RSS,1 CaP | 1.49 (0.15) | 1.35 (0.08) | 1.37 (0.06) | 1.39 (0.05) | 1.29 (0.05) | 1.35 (0.05) | 1.33 (0.06) | 1.20 (0.07) | 1.19 (0.09) | 0.011 |
| SS,2 CaP | 1.05 (0.16) | 1.32 (0.08) | 1.15 (0.07) | 1.16 (0.06) | 1.14 (0.06) | 1.07 (0.06) | 1.12 (0.06) | 1.12 (0.07) | 1.18 (0.09) | 0.16 |
| RSS,1 UA | 2.15 (0.21) | 2.05 (0.11) | 2.12 (0.08) | 1.95 (0.07) | 1.87 (0.07) | 1.85 (0.08) | 1.61 (0.08) | 1.85 (0.09) | 1.56 (0.13) | <0.001 |
| SS,2 UA | 0.94 (0.13) | 0.75 (0.06) | 0.76 (0.05) | 0.72 (0.05) | 0.70 (0.05) | 0.60 (0.05) | 0.60 (0.06) | 0.57 (0.06) | 0.59 (0.07) | <0.001 |
Models were adjusted for age, BMI, urinary creatinine, history of kidney stones, and study cohort (HPFS, NHS I, or NHS II).
aMED, alternate Mediterranean diet score; Ca, calcium; CaOx, calcium oxalate; CaP, calcium phosphate; Cit, citrate; Creat, creatinine; HPFS, Health Professionals Follow-up Study; K, potassium; Mg, magnesium; Na, sodium; NHS I, Nurses’ Health Study I; NHS II, Nurses’ Health Study II; Ox, oxalate; P, phosphorous; RSS, relative supersaturation; SS, supersaturation; UA, uric acid; V, urinary volume.
1
Measured by Mission Pharmacal.
2
Measured by Litholink.