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. Author manuscript; available in PMC: 2021 Nov 12.
Published in final edited form as: Nature. 2021 May 12;593(7860):580–585. doi: 10.1038/s41586-021-03533-z

Extended Data Figure 9. Energy expenditure and movement of wild-type versus Adipo-Alpl KO mice upon HFD.

Extended Data Figure 9.

(a) Indirect calorimetric measurement on wild-type vs Adipo-Alpl KO mice that had been on HFD for 4 weeks at 22 °C; n=7 mice for wild-type and 6 mice for Adipo-Alpl KO; the grey area indicates the dark period.

(b) Averaged respiration rates over 24 hours as measured in (a); n=7 mice for wild-type and 6 mice for Adipo-Alpl KO.

(c) Cumulative movement of mice over 24 hours; n=7 mice for wild-type and 6 mice for Adipo-Alpl KO.

Data are presented as means ± SEM. Statistical significance was calculated by either two-way ANOVA (a) or unpaired Student’s two-sided t-test (b and c).