Table 5.
Estimates of percent increase in striolar HCI per utricle
Time post-Tam | Striolar Tom+ HCI from Figure 6, Sox2 WT | Striolar Tom+ HCI from Figure 6, Sox2 CKO | Increase in Tom+ striolar HCI Sox2 CKO re. WT** | Estimated % Increase in striolar HCI number* |
---|---|---|---|---|
1 month | 13 | 46 | 33 | 9% |
4 months | 15 | 71 | 56 | 16% |
8 months | 15 | 91 | 76 | 21% |
* Estimates of % increase were calculated as follows: we counted, on average, 245 striolar HCII (Tom– or Tom+) per utricle (n = 3 mice at 4 months post-Tam). Based on the ratio of HCI to HCII in striola (1.47–1.00 from Desai et al., 2005), we estimated there are 360 striolar HCI per utricle. We added 360 to the number by which ES HCI increased after Sox2 CKO** and divided by 360 to determine the % increase.
** Difference between the second and third columns.